Endometriosis

Endometriosis is a condition in which cells that normally line the uterus grow outside of the uterine cavity. Endometriosis may cause debilitating symptoms including pain during menstruation (dysmenorrhea), non-menstrual pelvic pain, and pain with sexual intercourse (dyspareunia).

Endometriosis lesions can be found throughout the pelvis and abdomen, including on the ovaries and intestines. It is unknown what determines the location of endometriosis.

How common is this?
Is this normal? Abnormal?

Approximately 10% of women of reproductive age have endometriosis. Many of these women have significant symptoms that do not respond to oral contraceptives, the first-line therapy.

To diagnose endometriosis, a woman must undergo a surgical procedure called a laparoscopy. A non-invasive diagnostic for endometriosis does not exist.

It is common for women to experience some discomfort during their menstrual cycles. Moderate-to-severe pain that disrupts daily activities is not normal. Uncertainty around what is normal and abnormal pelvic pain can contribute to delayed diagnosis.

How Does Endometriosis Affect the Body?

Many women with endometriosis experience pelvic pain and pain with sexual intercourse (dyspareunia). A common association with endometriosis is infertility. Other effects of endometriosis, which can impact many organs, include fatigue and urinary and bowel symptoms. Estrogen, which is produced by the ovaries, contributes to the development and growth of endometriosis.

Standard Treatment Options

Standard treatment options for endometriosis include medical therapies and surgery. Some women report improved symptoms on hormonal contraceptives. GnRH agonists are injections that lower estrogen and manage the disease. This treatment is for short-term use due to bone mineral density loss, hot flushes, and other side effects from a low-estrogen state. Laparoscopy is a surgical procedure that may include the removal of visible endometriosis. While some women report improved symptoms with hysterectomy, the surgery does not remove all endometriosis and involves removal of the entire uterus, which leads to the loss of fertility. Despite multiple laparoscopies, some women still undergo a hysterectomy, which can involve major complications such as excessive bleeding and infection. Additional treatment options exist. All treatment decisions should be discussed with a healthcare provider.

Medical(other than pain medications)

  • Hormonal contraceptives
  • GnRH agonists

Surgical

  • Laprascopy
  • Hysterectomy

Turning Science into medicine

Too often, endometriosis is dismissed as simply “bad periods” or normal menstruation. At Myovant, we believe that women should be empowered to lead full, healthy lives. Millions of women across the world do not have this opportunity due to symptoms from endometriosis. This is why we are invested in driving women’s health forward and developing innovative treatments to improve the current standard of care.

Explore our purpose

Starting The Conversation

Talking to your healthcare provider or loved ones about endometriosis can be hard. We’re here to help facilitate the conversation so that women get the attention they need and deserve. Here are some helpful resources.

Advocacy Resources

The Endometriosis Association provides comprehensive education and community support to women with endometriosis.
Learn more at endometriosisassn.org

Endometriosis.org provides information and support to women suffering from endometriosis.
Learn more at endometriosis.org

The WorldWide EndoMarch is a growing community of patients and advocates fighting for endometriosis awareness and research.
Learn more at endomarchnews.org

The American College of Obstetricians and Gynecologists (ACOG) provides comprehensive resources on the symptoms, diagnosis, and current treatments of endometriosis.
Learn more at acog.org

Our Advocacy

We are dedicated to partnering across sectors to bring much-needed attention and innovation to women’s health.

Learn more about our Female Forward initiatives