Prostate cancer is cancer that starts in the prostate gland in men. Prostate cancer usually grows slowly and is confined, or localized, to the prostate gland. Cancer cells can grow beyond the prostate gland and spread to nearby tissues, also called metastasis.
Most prostate cancer is diagnosed while men are asymptomatic. Symptoms of metastatic prostate cancer may include weight loss, bone pain, fatigue, and urinary symptoms.
How Common Is this?
What are the Stages?
Prostate cancer is the second most common and fifth leading cause of cancer death in the world. Screening for prostate cancer may include a test for prostate-specific antigen (PSA) which can be elevated in the disease. The diagnosis of prostate cancer is based on a biopsy of the prostate.
Staging systems are used to describe how much a cancer has grown. This information is used to inform treatment decision for patients. There are four stages of prostate cancer. Stage 1 prostate cancer is confined (or localized) to the prostate, while stage 4 prostate cancer has grown beyond the prostate and is metastatic.
How does prostate cancer progress?
Prostate cancer does not always progress through the four stages of the disease. Metastatic prostate cancer most frequently spreads to the bone. Testosterone, which is produced by the testes, contributes to the growth of prostate cancer. Androgen deprivation therapy with gonadotropin-releasing hormone (GnRH) medications decreases testosterone and is the foundational therapy across multiple states of prostate cancer.
Turning Science Into Medicine
Millions of men live with prostate cancer. Many of these men receive androgen deprivation therapy to lower their testosterone, which drives prostate cancer. The most commonly prescribed treatment, an injection, can cause a hormonal flare with worsening clinical symptoms when started. At Myovant, we believe men should be empowered with treatment options. That is why we are committed to developing the first oral GnRH antagonist for prostate cancer.
Starting The Conversation
Whether you or a loved one has been diagnosed with prostate cancer, you are not alone. Here are some helpful resources to learn more about prostate cancer and connect with a community.
The Prostate Cancer Foundation (PCF) funds research to improve the prevention, detection, and treatment of prostate cancer.
Learn more at pcf.org
The Center for Disease Control and Prevention (CDC) provides helpful resources and statistics about prostate cancer diagnosis and treatment.
Learn more at cdc.gov
The Movember Foundation is an advocacy group focused on funding innovative research for men’s health, including prostate cancer, and raising awareness about men’s health.
Learn more at us.movember.com
The American Cancer Society (ACS) provides comprehensive resources on the causes, diagnosis, and treatments of prostate cancer.
Learn more at cancer.org